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Salvinorin A
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Salvinorin A : ウィキペディア英語版
Salvinorin A

Salvinorin A is the main active psychotropic molecule in ''Salvia divinorum'', a Mexican plant which has a long history of use as an entheogen by indigenous Mazatec shamans. Salvinorin A is considered a dissociative exhibiting atypically psychedelic effects.
It is structurally distinct from other naturally occurring hallucinogens (such as DMT, psilocybin, and mescaline) because it contains no nitrogen atoms; hence, it is not an alkaloid (and cannot be rendered as a salt) but a terpenoid.〔(【引用サイトリンク】url=http://www.salviaextract.com/blog/salvia-chemistry/ )〕 It also differs in subjective experience, compared to other hallucinogens, and has been described as dissociative.〔
Salvinorin A can produce psychoactive experiences in humans with a typical duration of action being several minutes to an hour or so, depending on the method of ingestion.〔
Salvinorin A is found with several other structurally related salvinorins. Salvinorin is a ''trans''-neoclerodane diterpenoid. It acts as a kappa opioid receptor agonist and is the first known compound acting on this receptor that is not an alkaloid.
== History ==

Salvinorin A was first described and named in 1982 by Alfredo Ortega and colleagues in Mexico. They used a combination of spectroscopy and x-ray crystallography to determine the chemical structure of the compound, which was shown to have a bicyclic diterpene structure.〔 Around the same time, Leander Julián Valdés III independently isolated the molecule as part of his PhD research, published in 1983.〔 Valdés named the chemical ''divinorum'', and also isolated an analog that he named divinorum B. The naming was subsequently corrected to salvinorin A and B after the work was published in 1984.〔 Valdés later isolated salvinorin C.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Salvinorin A」の詳細全文を読む



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